Acute generalized exanthematous pustulosis associated with 2 common medications: Hydroxyzine and benzocaine

Acute Generalized Exanthematous Pustulosis Associated with Tigecycline

Acute generalized exanthematous pustulosis (AGEP) is a severe and rare eruption that develops mostly from factors related to drugs. It is characterized by a fever and a pustular eruption on the erythematous skin with an acute onset and without follicular localization. Etiopathogenesis has not yet been fully explained. Although it is similar to pustular psoriasis, its clinical, historical and hi...

Acute generalized exanthematous pustulosis associated with paracetamol.

initially only with palmoplantar pustular lesions. Dermatology 6. Ramirez F, Fowell DJ, Puklavec M, Simmonds S, Mason D. 1992; 185: 276–280. Glucocorticids promote a Th2 cytokine response by CD4 T cells in 3. Patrizi A, Di Lernia V, Neri I, Gherlinzoni F. Eosinophilic pustular vitro. J Immunol 1996; 156: 2406–2412. folliculitis (Ofuji’s disease) and non-Hodgkin lymphoma. Acta Derm Venereol (Sto...

[Acute generalized exanthematous pustulosis associated with diltiazem].

Acute generalized exanthematous pustulosis (AGEP) usually presents with the acute appearance of oedematous and erythematous lesions, on which multiple sterile pustules appear, associated with fever. Almost 90% of cases are associated with drugs, with antibiotics (penicillins and macrolides) being the most frequent causative agents. We describe a 36-year-old female patient, which started diltiaz...

Acute generalized exanthematous pustulosis

Acute generalized exanthematous pustulosis with mephenesin balm.

Mephenesin is an aromatic glycerol ether which decreases polysynaptic transmission in the spinal cord and brain stem. It is used as a skeletal muscle relaxant in the treatment of multiple sclerosis, Parkinson’s disease or acute muscle strain [1,2]. Mephenesin is associated to methyl nicotinate in the Décontractyl Balm. The methyl nicotinate has a rubifacient effect. Usually, the Décontractyl Ba...